Strain Information

Name MLC610   View On Wormbase
Species C. elegans
Genotypecah-3(luc28[3' UTRmutant, delta mir-791 binding sites])
Descriptionluc28 removes mir-791 binding sites in the cah-3 3'UTR. luc28 worms show less response towards a gradual increase in CO2 concentration from 0-5% as compared to N2 animals. Reference: Drexel T, et al. Genes Dev. 2016 Sep 15;30(18):2042-2047.
MutagenCrispr/Cas9
Outcrossedx0
Made byDrexel Tanja
Laboratory MLC
Reference Drexel T, Mahofsky K, Latham R, Zimmer M, Cochella L. 2016. Neuron-type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans. Genes Dev 10.1101/gad.287904.116.
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