Strain Information

Name MCJ219   View On Wormbase
Species C elegans
Genotypesup-26(cdb99) nhl-2(cdb100) III; egl-1(cdb97) V.
Descriptionnhl-2(cdb100) contains engineered mutations in the mir-35 binding site in the nhl-2 3’UTR region making the sequence complementary to the mir-35(cdb4) variant. egl-1(cdb97) contains engineered mutations in mir-35 binding site in the egl-1 3’UTR region making the sequence complementary to the mir-35(cdb4) variant. Slightly reduced brood size at 25C. Reference: Donnelly BF, et al. (2022). Cell Reports.
MutagenNo mutagen
Outcrossedx0
Made byBing Yang
Laboratory MCJ
Reference Donnelly, B.F., Yang, B., Grimme, A.L., Vieux, K.-F., Liu, C.-Y., Zhou, L., and McJunkin, K. (2022). The developmentally-timed decay of an essential microRNA family is seed sequence-dependent. BioRxiv 2021.11.19.469346.
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