Strain Information
Name | MCJ219 View On Wormbase |
---|---|
Species | C elegans |
Genotype | sup-26(cdb99) nhl-2(cdb100) III; egl-1(cdb97) V. |
Description | nhl-2(cdb100) contains engineered mutations in the mir-35 binding site in the nhl-2 3’UTR region making the sequence complementary to the mir-35(cdb4) variant. egl-1(cdb97) contains engineered mutations in mir-35 binding site in the egl-1 3’UTR region making the sequence complementary to the mir-35(cdb4) variant. Slightly reduced brood size at 25C. Reference: Donnelly BF, et al. (2022). Cell Reports. |
Mutagen | No mutagen |
Outcrossed | x0 |
Made by | Bing Yang |
Laboratory | MCJ |
Reference | Donnelly, B.F., Yang, B., Grimme, A.L., Vieux, K.-F., Liu, C.-Y., Zhou, L., and McJunkin, K. (2022). The developmentally-timed decay of an essential microRNA family is seed sequence-dependent. BioRxiv 2021.11.19.469346. |
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