Strain Information
| Name | LP177 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | unc-119(ed3) III; che-12(cp26[GFP + LoxP + unc-119(+) + LoxP]) V. |
| Description | Entire che-12 coding sequence deleted and replaced with GFP. This produced a phenotype that is more penetrant than that reported for the original che-12 strain, which introduced a nonsense mutation midway through the coding region. Short amphid and phasmid cilia. Defective chemotaxis to NaCl. Dye-filing defective. Reference: Das A, et al. Mol Biol Cell. 2015 Nov 15;26(23):4248-64. |
| Mutagen | N/A |
| Outcrossed | x0 |
| Made by | Daniel Dickinson |
| Laboratory | LP |
| Reference | Das A, Dickinson DJ, Wood CC, Goldstein B, Slep KC. Crescerin uses a TOG domain array to regulate microtubules in the primary cilium. Mol Biol Cell. 2015 Nov 15;26(23):4248-64. doi: 10.1091/mbc.E15-08-0603. |
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