Strain Information
Name | LBV5 View On Wormbase |
---|---|
Species | C. elegans |
Genotype | str-217(ejd1) V. |
Description | DEET-resistant. ejd1 is a CRISPR/Cas9-induced mutation causing a predicted frame-shift in the first exon. WT (affected sequence between arrows):GCTTTTATTCCAAAAAACTCTCTCCCGCGTCG>CTGCTCCAA ejd1: GCTTTTATTCCAAAAAACTCTCTCCCGCGTCG>AAAAAAAA Reference: Dennis EJ, et al. Nature. 2018 Oct;562(7725):119-123. |
Mutagen | CRISPR targeted mutation |
Outcrossed | x0 |
Made by | Emily Dennis |
Laboratory | LBV |
Reference | Dennis EJ, Dobosiewicz M, Jin X, Duvall LB, Hartman PS, Bargmann CI, and Vosshall LB. A natural variant and engineered mutation in a GPCR promote DEET resistance in C. elegans (2018) Nature 562, 119-123. |
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