Strain Information
| Name | KQ2841 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | aat-1(ft1003) IV. |
| Description | sf1003 is a CRISPR-engineered deletion in aat-1. aat-1(sf1003) mutants show elevated pumping rates and enhanced learning capacity compared to well-fed wild type animals (similar to nkat-1 mutants). Reference: Lin L, et al. Genes Dev. 2020 Aug 1;34(15-16):1033-1038. doi: 10.1101/gad.339119.120. PMID: 32675325. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x4 |
| Made by | Lin Lin |
| Laboratory | KQ |
| Reference | Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter. Lin L, Lemieux GA, Enogieru OJ, Giacomini KM, Ashrafi K. Genes Dev. 2020 Aug 1;34(15-16):1033-1038. doi: 10.1101/gad.339119.120. PMID: 32675325 |
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