Laboratory Information
| Name | KQ View on WormBase |
|---|---|
| Allele designation | ft |
| Head | Kaveh Ashrafi |
| Institution | University of California, San Francisco, CA |
| Address | 600 16th Street, Genentech Hall N416 Ashrafi Lab San Francisco 94158 United States |
| Website | http://ashrafilab.ucsf.edu/index.html |
| Gene classes | spsb tctn vms lpo |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| KQ1323 | akt-2(tm812) sgk-1(ft15) X. | C. elegans | ft15 allele is a gain-of-function mutation in sgk-1. sgk-1(ft15) mutants have normal body size and normalize the small body size of rict-1 loss-of-function mutants. Reference: Jones KT, et al. PLos Biol. 2009 Mar 3;7(3):e60. doi: 10.1371/journal.pbio.1000060. PMID: 19260765. |
| KQ1366 | rict-1(ft7) II. | C. elegans | Small, slightly developmentally delayed. Increased Nile Red staining. Slightly more severe than mg360. |
| KQ1564 | sgk-1(ft15) X. | C. elegans | ft15 allele is a gain-of-function mutation in sgk-1. sgk-1(ft15) mutants have normal body size and normalize the small body size of rict-1 loss-of-function mutants. Reference: Jones KT, et al. PLos Biol. 2009 Mar 3;7(3):e60. doi: 10.1371/journal.pbio.1000060. PMID: 19260765. |
| KQ2841 | aat-1(ft1003) IV. | C. elegans | sf1003 is a CRISPR-engineered deletion in aat-1. aat-1(sf1003) mutants show elevated pumping rates and enhanced learning capacity compared to well-fed wild type animals (similar to nkat-1 mutants). Reference: Lin L, et al. Genes Dev. 2020 Aug 1;34(15-16):1033-1038. doi: 10.1101/gad.339119.120. PMID: 32675325. |
| KQ6 | rict-1(mg360) II. | C. elegans | Small, slightly developmentally delayed. Increased Nile Red staining. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| ft15 | Allele | substitution | |
| ft7 | Allele | substitution |