Strain Information
| Name | KK1254 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | par-2(it315[mCherry::par-2]) III. |
| Description | par-2(it315) exhibits a weak maternal effect sterility, suggesting that the tag reduces the protein activity. Note, however, that double homozygous mutants of it315 with pkc-3(it309) or par-6(it310) exhibited partially penetrant and variable maternal effect lethality and maternal effect sterility that was stronger than it315 alone. Thus, although the GFP tags on pkc-3 and par-6 show no effect in an otherwise wild-type background, they do seem to somewhat compromise the activity of the proteins they tag. Made in N2 background. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Ken Kemphues |
| Laboratory | KK |
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