Strain Information

Name KK1254   View On Wormbase
Species C. elegans
Genotypepar-2(it315[mCherry::par-2]) III.
Descriptionpar-2(it315) exhibits a weak maternal effect sterility, suggesting that the tag reduces the protein activity. Note, however, that double homozygous mutants of it315 with pkc-3(it309) or par-6(it310) exhibited partially penetrant and variable maternal effect lethality and maternal effect sterility that was stronger than it315 alone. Thus, although the GFP tags on pkc-3 and par-6 show no effect in an otherwise wild-type background, they do seem to somewhat compromise the activity of the proteins they tag. Made in N2 background.
Made byKen Kemphues
Laboratory KK
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