Strain Information
| Name | KG421 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | gsa-1(ce81) I. |
| Description | Coordinated hyperactive locomotion. Hypersensitive to mechanical stimuli. Most mature adults have vulval bump. Mature animals are slightly short and egl-d. Terminal phenotype is usually bag of worms. Population tends to severely crash within 2-3 weeks of starvation. Dominant, gain-of-function allele. Heterozygotes are difficult to distinguish from homozygotes. Mutation is R182C. This same mutation causes constitutive Gs activity in vertebrates. Sequence in WT: CCT TCG GTG TCG. Sequence in ce81: CCT TCG GTG TTG. |
| Mutagen | No mutagen |
| Outcrossed | x5 |
| Laboratory | KG |
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