Variation Information: ce81

Namece81 View on WormBase
Species C. elegans
Genetic positionI:-16.97 +/- 0.000 cM
Genomic positionI: 1071691..1071691
Protein change Substitution

Strains carrying this variation

Strain Genotype Species Description
KG421 gsa-1(ce81) I. C. elegans Coordinated hyperactive locomotion. Hypersensitive to mechanical stimuli. Most mature adults have vulval bump. Mature animals are slightly short and egl-d. Terminal phenotype is usually bag of worms. Population tends to severely crash within 2-3 weeks of starvation. Dominant, gain-of-function allele. Heterozygotes are difficult to distinguish from homozygotes. Mutation is R182C. This same mutation causes constitutive Gs activity in vertebrates. Sequence in WT: CCT TCG GTG TCG. Sequence in ce81: CCT TCG GTG TTG.