Strain Information
| Name | JK6011 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | lst-1(q1032[*q1004]) I. |
| Description | q1004[LST-1::3xV5] is the CRISPR-engineered insertion of a 3xV5 tag at the C-terminus of the endogenous lst-1 locus. q1032 is the CRISPR-engineered mutation C260S & C263S in the Zn finger domain of LST-1 (Haupt et al., 2019) in the q1004 background. Reference: Haupt KA, et al. Development. 2019 Oct 17;146(20):dev181644. doi: 10.1242/dev.181644. PMID: 31515205. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x2 |
| Made by | Brandon Taylor |
| Laboratory | JK |
| Reference | Haupt KA, Enright AL, Ferdous AS, Kershner A, Shin H, Wickens M, and Kimble J. (2019) The molecular basis of LST-1 self-renewal activity and its control of stem cell pool size. Development, 146(20). |
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