Strain Information

Name JK2505   View On Wormbase
Species C. elegans
Genotypecyd-1(q626) II; him-5(e1490) V.
DescriptionTemperature-sensitive allele of cyd-1. Phenotypically wild-type at 15C. At 25C, approximately one-third of q626 hermaphrodites were missing one distal tip cell (DTC) and approximately one-half of q626 males were missing the linker cell (LC). q626 also feminizes the XO gonad. q626 affects the production of SGP daughters in both sexes. There is also a maternal component since the mutant phenotype is almost fully penetrant in offspring of homozygous mothers, but less penetrant in offspring of heterozygous mothers. Reference: Tilmann C & Kimble J. Dev Cell. 2005 Oct;9(4):489-99.
Made byFinn Hugo Markussen
Laboratory JK
Reference Tilmann, C. and J. Kimble (2005) Cyclin D regulation of a sexually dimorphic asymmetric cell division. Developmental Cell 9, 489-499.
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