Strain Information

Name HS3545   View On Wormbase
Species C. elegans
GenotypeosIs158 II; ieSi58 IV.
DescriptionosIs158 [eft-3p::ccvTIR-1(F79G)::mRuby] single copy inserted into ttTi5605 on LG II. ieSi58 [eft-3p::degron::GFP::unc-54 3'UTR + Cbr-unc-119(+)] IV. This strain expresses the improved version of TIR1 used for improved auxin-inducible degradation (AID2) technology. Reference: Negishi T, et al. Genetics. 2021 Dec 2;iyab218. doi: 10.1093/genetics/iyab218.
Made byTakefumi Negishi
Laboratory HS
Reference Yesbolatova et al. The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice. Nature Communications 11, 5701(2020)
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