Strain Information
| Name | HP23 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | sos-1(pd9) V. |
| Description | sos-1(pd9) is a gain-of-function allele causing a C662Y substitution within the Ras exchange motif of SOS-1. Originally isolated as a suppressor of sem-5(n1619) lethality. Single mutants appear wild-type. Reference: Wooller A & Hopper N. (2014) European Worm Meeting. (Anyone using this allele may cite Neil Hopper as a personal communication based on this meeting abstract.) |
| Mutagen | EMS |
| Outcrossed | x0 |
| Made by | Neil Hopper |
| Laboratory | UP |
| Reference | Wooller, A., & Hopper, N. (2004). A SCREEN FOR SUPPRESSORS OF SEM-5 LETHALITY IDENTIFIES TWO GAIN OF FUNCTION SOS-1 ALLELES presented in European Worm Meeting. Anyone using this allele may cite Neil Hopper as a personal communication based on this meeting abstract. |
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