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|Species|| C. elegans |
|Description||sos-1(pd9) is a gain-of-function allele causing a C662Y substitution within the Ras exchange motif of SOS-1. Originally isolated as a suppressor of sem-5(n1619) lethality. Single mutants appear wild-type. Reference: Wooller A & Hopper N. (2014) European Worm Meeting. (Anyone using this allele may cite Neil Hopper as a personal communication based on this meeting abstract.)|
|Made by||Neil Hopper|
|Reference ||Wooller, A., & Hopper, N. (2004). A SCREEN FOR SUPPRESSORS OF SEM-5 LETHALITY IDENTIFIES TWO GAIN OF FUNCTION SOS-1 ALLELES presented in European Worm Meeting.
Anyone using this allele may cite Neil Hopper as a personal communication based on this meeting abstract.|