Strain Information
| Name | HA3971 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | tdp-1(tgx286[hTARDBP]) I. |
| Description | No obvious phenotype. C. elegans tdp-1 coding sequences were completely removed and replaced with sequences encoding human TDP43 optimized for expression in C. elegans. Three synthetic introns are introduced into the humanized locus. Reference: Lins J, et al. Generation of a C. elegans tdp-1 null allele and humanized TARDBP containing human disease-variants. MicroPubl Biol. 2023 Jun 6;2023:10.17912/micropub.biology.000693. doi: 10.17912/micropub.biology.000693. PMID: 37351305. |
| Mutagen | No mutagen |
| Outcrossed | x4X |
| Made by | InVivo Biosystems/Nemametrix and Hart lab |
| Laboratory | HA |
| Reference | 10.17912/micropub.biology.000693 |
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