Strain Information

Name GS9801   View On Wormbase
Species C. elegans
Genotyperde-1(ar660) V.
Descriptionrde-1(ar660)[rde-1(flexon)]. 9th intron of rde-1 replaced with a flexon - an artificial exon flanked by artificial introns that each contain a lox2272 site (a flexon). Severely reduces rde-1 function, function can be restored upon excision of the flexon by Cre recombinase. Reference: Shaffer JM & Greenwald I. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2117451119. doi: 10.1073/pnas.2117451119. PMID: 35027456.
MutagenCrispr/Cas9
Outcrossedx0
Made byJustin Shaffer
Laboratory GS
Reference Shaffer JM, Greenwald I. Floxed exon (Flexon): A flexibly positioned stop cassette for recombinase-mediated conditional gene expression. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2117451119. doi: 10.1073/pnas.2117451119. PMID: 35027456; PMCID: PMC8784106.
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