Strain Information
| Name | GS9801 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | rde-1(ar660) V. |
| Description | rde-1(ar660)[rde-1(flexon)]. 9th intron of rde-1 replaced with a flexon - an artificial exon flanked by artificial introns that each contain a lox2272 site (a flexon). Severely reduces rde-1 function, function can be restored upon excision of the flexon by Cre recombinase. Reference: Shaffer JM & Greenwald I. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2117451119. doi: 10.1073/pnas.2117451119. PMID: 35027456. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Justin Shaffer |
| Laboratory | GS |
| Reference | Shaffer JM, Greenwald I. Floxed exon (Flexon): A flexibly positioned stop cassette for recombinase-mediated conditional gene expression. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2117451119. doi: 10.1073/pnas.2117451119. PMID: 35027456; PMCID: PMC8784106. |
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