Strain Information
| Name | GS8729 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | arSi12. |
| Description | arSi12 [mex-5p::ERK::KTR::GFP(smu-1 introns)::T2A::mCherry::his-11::tbb-2 3'UTR]. arSi12 is a single-copy CRISPR/Cas9-engineered insertion expressing a fluorescent protein (ERK::KTR::GFP) that reports MPK-1 kinase activity in the germline. A nuclear histone marker is co-expressed (mCherry::H2B). Reference: de la Cova C, et al. Developmental Cell. 2017 Vol. 42(5):542-553. |
| Mutagen | CRISPR/Cas9 homologous recombination |
| Outcrossed | x0 |
| Made by | Claire de la Cova |
| Laboratory | GS |
| Reference | de la Cova, C., Townley, R., Regot, S., and Greenwald, I. A real-time biosensor for ERK activity reveals signaling dynamics during C. elegans cell fate specification. Developmental Cell. 2017 Vol. 42(5):542-553. doi: 10.1016/j.devcel.2017.07.014. PMID: 28826819. |
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