Strain Information
| Name | GS8255 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | arTi101. |
| Description | arTi101 [lin-31p::ERK::KTR(S43A, T55A, S62A)::mClover::T2A::mCherry::his-11::unc-54 3'UTR + rps-27p::NeoR::unc-54 3'UTR]. Superficially wild-type. arTi101 transgene is a single-copy transposon insertion expressing a mutant, unphosphorylated form of a fluorescent protein (ERK::KTR::mClover) that reports MPK-1 kinase activity in vulval precursor cells (VPCs). A nuclear histone marker is co-expressed (mCherry::H2B). Use arTi101 as a negative control for transgene arTi85. Reference: de la Cova C, et al. Developmental Cell. 2017 Vol. 42(5):542-553. |
| Mutagen | Mos1 transposon |
| Outcrossed | x0 |
| Made by | Claire de la Cova |
| Laboratory | GS |
| Reference | de la Cova, C., Townley, R., Regot, S., and Greenwald, I. A real-time biosensor for ERK activity reveals signaling dynamics during C. elegans cell fate specification. Developmental Cell. 2017 Vol. 42(5):542-553. doi: 10.1016/j.devcel.2017.07.014. PMID: 28826819. |
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