Strain Information

Name GIN101   View On Wormbase
Species C. elegans
Genotypethoc-2(tm1310) III/hT2[bli-4(e937) let-?(q782) qIs48] (I;III).
DescriptionHomozygous sterile allele balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP sterile homozygotes (tm1310 is maternally rescued; progeny of non-GFP animals fail to give viable progeny). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Castellano-Pozo, García-Muse T, Aguilera A. 2012 R-loops cause replication impairment and genome instability during meiosis. EMBO Rep. 13(10): 923-9.
Made byM. Castellano-Pozo
Laboratory GIN
Sign in or register an account if you want to order this strain.