Strain Information
| Name | GE2453 View On Wormbase Documentation for GE2453 t1900 perm-5 |
|---|---|
| Species | C. elegans |
| Genotype | xpf-1(e1487) II; unc-24(e138) perm-5(t1900)/nT1[let (m435)] IV; dpy-11(e224)/nT1[let (m435)] V. |
| Description | Maternal effect lethal mutation linked to unc-24(e138) and pseudolinked to dpy-11(e224), and balanced by recessive lethal translocation. Heterozygotes are WT and segregate WT, arrested nT1 aneuploids, arrested nT1 homozygotes, and viable DpyUnc t1900 homozygotes that produce dead embryos. GE2453 is also homozygous for xpf-1(e1487) so that male progeny are segregated. Pick WT and check for correct segregation of progeny to maintain. Please reference Li-Leger et al., G3 11(12) 2021 in any work resulting from use of this mutation. xpf-1 previously known as him-9. |
| Mutagen | EMS |
| Outcrossed | x1 |
| Made by | Vancouver KO Group |
| Laboratory | VC |
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