Strain Information

Name EU626   View On Wormbase
Species C. elegans
Genotyperfl-1(or198) III.
DescriptionTemperature sensitive maternal effect lethal mutation in F11H8.1 (Nedd8 activating enzyme). Permissive temperature is 15C, restrictive temperature is 25C. Embryos layed at restrictive temperature have spindle-orientation defects due to the mis-localization of MEI-1/MEI-2 to the mitotic spindle. Additionally, ectopic cleavage furrows are initiated during cytokinesis, and cell-cycle delays are apparent during interphase.
Made byDanielle Hamill
Laboratory EU
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