Strain Information
| Name | EU626 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | rfl-1(or198) III. |
| Description | Temperature sensitive maternal effect lethal mutation in F11H8.1 (Nedd8 activating enzyme). Permissive temperature is 15C, restrictive temperature is 25C. Embryos layed at restrictive temperature have spindle-orientation defects due to the mis-localization of MEI-1/MEI-2 to the mitotic spindle. Additionally, ectopic cleavage furrows are initiated during cytokinesis, and cell-cycle delays are apparent during interphase. |
| Mutagen | EMS |
| Outcrossed | x6 |
| Made by | Danielle Hamill |
| Laboratory | EU |
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