Strain Information

Name EU1516   View On Wormbase
Species C. elegans
Genotypeaph-1(or28)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III.
Descriptionor28 is a non-conditional maternal-effect embryonic lethal mutant ; the anterior pharynx is absent. and embryonic lethality is 100% penetrant. Pick single WT heterozygous hermaphrodites to maintain strain; these hets produce 11/16 dead embryos due to aneuploidy from translocation segregation and lethal homozygous hT2. The homozygous or28 hermaphrodites produce all dead embryos with defective pharyngeal development. or28 is a G to D mis-sense mutation at amino acid position 123. Strain produces lots of males due to him-8(ec56).
Made byBruce Bowerman
Laboratory EU
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