Strain Information
| Name | EU1381 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | act-2(or295) V. |
| Description | Weakly semi-dominant, temperature sensitive, embryonic lethal mutant. 38% of embyros produced by homozygous mothers at 15C will hatch; 2% produced at 26C will hatch. Mutation is semi-dominant at 26C: 12% of embryos produced by heterozygous mothers hatched at 26C, and about 25% of the survivors were or295/or295, indicating the lethality is semi-dominant and maternal. Mutant embyros exhibit excess cortical actomyosin contractility (extra furrows and protrusions) in early embryonic cells, during interphase and most of mitosis. or295 is a gga to aga substitution (G16R). |
| Mutagen | EMS |
| Outcrossed | x8 |
| Made by | John Willis |
| Laboratory | EU |
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