Strain Information
| Name | EU1296 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | him-8(e1489) IV; act-2(or621) V. |
| Description | Strongly semi-dominant, temperature sensitive, embryonic lethal mutant. 40% of embyros produced by homozygous mothers at 15C will hatch; 0% produced at 26C will hatch. Mutation is semi-dominant at 26C: 85% of embyros produced by heterozygous mothers hatched at 26C. Mutant embryos exhibit excess coritical actomyosin contractility (extra furrows and protrusions) in early embryonic cells; during interphase and most of mitosis. Throws males. or621 is a tcc to gcc substitution (S15A). |
| Mutagen | ENU |
| Outcrossed | x4 |
| Made by | John Willis |
| Laboratory | EU |
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