Strain Information
| Name | EL694 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | pup-4(om140) II. |
| Description | pup-4/F43E2.1. Maintain at 15-20C. Homozygotes produce <1% sterile individuals at 25C after multiple generations. ~10% of fertile individuals contain one infertile gonad arm. om140 is a CRISPR-engineered internal deletion removing most of the pup-4 coding sequence. Reference: Kelley L, et al. Development. 2024 Oct 7;228(2):iyae120. doi: 10.1093/genetics/iyae120. PMID: 39067069. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x4 |
| Made by | Leanne Kelley |
| Laboratory | EL |
| Reference | Kelley, L.H., I.V. Caldas, M.T. Sullenberger, K.E. Yongblah, A.M. Niazi, A. Iyer, Y. Li, P.M. Tran, E. Valen, Y.H. Ahmed-Braimah, E.M. Maine (2024) Poly(U) polymerase activity in C. elegans regulates abundance and tailing of sRNA and mRNA. Genetics, doi:10.1093/genetics/iyae120. |
Sign in
or
register an account if you want to order this strain.