Strain Information
| Name | Db11 View On Wormbase |
|---|---|
| Species | Serratia marcescens |
| Genotype | Serratia marcescens. |
| Description | [NOTE: This strain was classified as BSL2 by the U of MN Institutional Biosafety Committee (IBC). The CGC does not have the permits required by the University to work with the strain in our lab space or distribute the strain.] Bacteria. Former CGC designation IGX2. Tetracycline, streptomycin and kanamycin resistant. A spontaneous mutant resistant to streptomycin isolated from Db10. Serratia marcescens is a Gram-negative bacterium with a broad host range. S. marcescens is an opportunistic human pathogen and kills C. elegans upon colonization of the nematode intestine. Strain Db11 is a non-pigmented strain that is used to infect the nematode Caenorhabditis elegans in an infection-based model for studying host-pathogen interactions. See Flyg, Kenne K, Boman HG: Insect pathogenic properties of Serratia marcescens: phage-resistant mutants with a decreased resistance to Cecropia immunity and a decreased virulence to Drosophila. CGC #5819. References: Kurz CL, et al. EMBO J. 2003 Apr 1;22(7):1451-60. Iguchi A, et al. Genome Biol Evol. 2014 Aug;6(8):2096-110. J. Gen. Microbiol. 1980; 120: 173-181. Biosafety Level: BSL-1. |
| Mutagen | |
| Laboratory | IG |
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