Strain Information

Name DWP219   View On Wormbase
Species C. elegans
Genotypedaam-1(ups39) V.
DescriptionSuperficially wild-type. ups39 is a CRISPR-engineered deletion within daam-1. daam-1(ups39) encodes an in-frame stop codon near the start of its FH2-coding sequence, and a 1-nt frame shift due to the LoxP site, and is thus predicted encode a non-functional formin. Reference: Sundaramurthy S, et al. Cytoskeleton (Hoboken). 2020 Oct;77(10):422-441. doi: 10.1002/cm.21639. PMID: 33103378.
Made byDavid Pruyne
Laboratory DWP
Reference S Sundaramurthy, S Votra, A Laszlo, T Davies, D Pruyne. FHOD-1 is the only formin in Caenorhabditis elegans that promotes striated muscle growth and Z-line organization in a cell-autonomous manner. Cytoskeleton (Hoboken). 2020 Oct;77(10):422-441. doi: 10.1002/cm.21639.
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