Strain Information
| Name | DWP219 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | daam-1(ups39) V. |
| Description | Superficially wild-type. ups39 is a CRISPR-engineered deletion within daam-1. daam-1(ups39) encodes an in-frame stop codon near the start of its FH2-coding sequence, and a 1-nt frame shift due to the LoxP site, and is thus predicted encode a non-functional formin. Reference: Sundaramurthy S, et al. Cytoskeleton (Hoboken). 2020 Oct;77(10):422-441. doi: 10.1002/cm.21639. PMID: 33103378. |
| Mutagen | CRISPR-Cas9 |
| Outcrossed | x6 |
| Made by | David Pruyne |
| Laboratory | DWP |
| Reference | S Sundaramurthy, S Votra, A Laszlo, T Davies, D Pruyne. FHOD-1 is the only formin in Caenorhabditis elegans that promotes striated muscle growth and Z-line organization in a cell-autonomous manner. Cytoskeleton (Hoboken). 2020 Oct;77(10):422-441. doi: 10.1002/cm.21639. |
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