Laboratory Information

NameDWP View on WormBase
Allele designationups
HeadDavid William Pruyne
InstitutionSUNY-UMU, Syracuse, NY
Address Department of Cell and Developmental Biology
107 Weiskotten Hall
766 Irving Avenue
Syracuse 13210
United States
Website https://www.pruynelab.org/
Gene classes daam 

Strains contributed by this laboratory

Strain Genotype Species Description
DWP219 daam-1(ups39) V. C. elegans Superficially wild-type. ups39 is a CRISPR-engineered deletion within daam-1. daam-1(ups39) encodes an in-frame stop codon near the start of its FH2-coding sequence, and a 1-nt frame shift due to the LoxP site, and is thus predicted encode a non-functional formin. Reference: Sundaramurthy S, et al. Cytoskeleton (Hoboken). 2020 Oct;77(10):422-441. doi: 10.1002/cm.21639. PMID: 33103378.
DWP294 rhIs2. C. elegans rhIs2 [pat-3::HA::GFP]. rhIs2 contains cosmid-derived full-length pat-3, including 5 kb 5’UTR and 1 kb 3’ UTR, with HA and GFP(S65C) tags inserted prior to the pat-3 stop codon. Reference: Plenefisch JD, et al. Development. 2000 127(6):1197-207. doi: 10.1242/dev.127.6.1197.
DWP3 qaIs8001. C. elegans qaIs8001 [fhod-1::GFP + unc-119(+)]. Integrated functional translational FHOD-1::GFP fusion. Superficially wild-type. Reference: Mi-Mi L, et al. J Cell Biol. 2012 Jul 9;198(1):87-102. doi: 10.1083/jcb.201202053.
This laboratory hasn't submitted any alleles to the CGC.