|Name||DQM935 View On Wormbase|
|Genotype||bmdSi245 I; fos-1(bmd138[fos-1p::LoxP::GFP::FOS-1]) V.|
|Description||bmdSi245 [^SEC^lin-29p::mKate2-STOP-STOP-DAMc1::VHH4GFP] I. Pick Rollers to maintain. Wild-type growth. NanoDam toolkit will allows identification of direct genomic targets of TFs as well as chromatin modifiers. In this system, Dam methylase is fused with a binding reagent, an anti-GFP nanobody (vhhGFP4). Thus, genome-wide profiling can be achieved by combining cell type-specific Dam::vhhGFP4 fusion constructs with GFP knock-in alleles.|
|Made by||Yutong Xiao|
|Reference||We are going to have a pre-print describing a new DamID-based approach, called NanoDam-ID in C. elegans, for genome-wide profiling targets, collaborating with Dr. Callista Yee and Dr. Michalis Barkoulas. Mechanisms of this tool is described below (other reason).|
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