Strain Information
| Name | DLS1004 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | vit-6(rhd332) IV; vit-5(rhd322) vit-4(rhd321) vit-3(rhd320) vit-2(ok3211) vit-1(ok2616) X. |
| Description | Multiple mutations were simultaneously introduced into the vit-3, vit-4, and vit-5 loci using a single crRNA to produce vit-5(rhd322[T391E, L392F, A393*]), vit-4(rhd321[T391E, L392F, A393*]), and vit-3(rhd320[T391E, L392F, A393*]). A similar strategy was used to create vit-6(rhd332[S320F, W322*]). Reference: Macharios MM, et al. MicroPubl Biol. 2025 Sep 10;2025:10.17912/micropub.biology.001789. doi: 10.17912/micropub.biology.001789. PMID: 41018027. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Monica Macharios and Yasmine Hernandez |
| Laboratory | DLS |
| Reference | Macharios MM, Hernandez YD, Breen PC, Dowen RH. Loss of the vitellogenins confers a fitness disadvantage but does not impact brood size in C. elegans. MicroPubl Biol. 2025 Sep 10;2025:10.17912/micropub.biology.001789. doi: 10.17912/micropub.biology.001789. PMID: 41018027; PMCID: PMC12461288. |
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