Strain Information

Name DE12   View On Wormbase
Species C. elegans
Genotypesup-46(qa710) I.
DescriptionSuperficially WT. Suppressor of gna-2. Reduced brood counts at all temperatures (very strongly reduced at 26C). Exhibits mating-dependent progressive hermaphrodite sterility. Reduced embryo survival following heat shock.
MutagenEMS
Outcrossedx10
Made byAldis Krizus
Laboratory DE
Reference Wendy L Johnston, Aldis Krizus and James W Dennis, (2006). The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo. BMC Biol, 4, 35. doi:10.1186/1741-7007-4-35 Wendy L. Johnston, Aldis Krizus, Arun K. Ramani, Wade Dunham, Ji Young Youn, Andrew G. Fraser, Anne-Claude Gingras and James W. Dennis, (2017). C. elegans SUP-46, an HNRNPM family RNAbinding protein that prevents paternally-mediated epigenetic sterility BMC Biology 15:61 doi: 10.
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