Strain Information
| Name | DCR8892 View On Wormbase |
|---|---|
| Species | C elegans |
| Genotype | olaEx5331. |
| Description | olaEx5331 [rab-3p::HYlight-RA + elt-7p::mCherry]. Pick mCherry+ animals to maintain. Pan-neuronal expression of HYlight-RA, a reduced affinity version of the FBP biosensor that does not respond to changes in concentration of the FBP metabolite during hypoxia in vivo. Can be used as a negative control for HYlight sensor in strain DCR8881. Reference: Wolfe AD, et al. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2314699121. doi: 10.1073/pnas.2314699121. PMID: 38198527. |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | Aaron Wolfe |
| Laboratory | DCR |
| Reference | Wolfe AD, Koberstein JN, Smith CB, Stewart ML, Gonzalez IJ, Hammarlund M, Hyman AA, Stork PJS, Goodman RH, Colón-Ramos DA. Local and dynamic regulation of neuronal glycolysis in vivo. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2314699121. doi: 10.1073/pnas.2314699121. Epub 2024 Jan 10. PMID: 38198527; PMCID: PMC10801914. |
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