Strain Information

Name DCR5765   View On Wormbase
Species C. elegans
Genotypeatg-4.2(ola316) IV.
DescriptionDominant negative allele of autophagy protease atg-4.2. Animals appear slightly dumpy. In neurons, autophagic vacuoles accumulate abnormally in the soma. Reference: Hill SE, et al. Dev Cell. 2019 Mar 8. pii: S1534-5807(19)30104-2.
Made bySarah Hill
Laboratory DCR
Reference Hill, SE, Kauffman, K, Krout, M, Richmond JE, Melia, T, Colón-Ramos, DA (2019). “Maturation and Clearance of Autophagosomes in Neurons Depends on a Specific Cysteine Protease Isoform, ATG-4.2.” Developmental Cell,
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