Strain Information
| Name | COP2412 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | atg-9(ola511[delta AP]) V. |
| Description | ola511 is aCRISPR-engineered allele deleting a conserved sorting motif in ATG-9, causing a 2- to 3-fold decrease in LGG-1-containing puncta (and therefore autophagosomes) in the AIY neurites. Reference: Yang S, et al. Neuron. 2022 Mar 2;110(5):824-840.e10. |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | InVivo Biosystems |
| Laboratory | DCR |
| Reference | Yang, S., Park, D., Manning, L., Hill, S. E., Cao, M., Xuan, Z., ... & Colón-Ramos, D. A. (2022). Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9. Neuron, 110(5), 824-840. |
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