Strain Information

Name COP2412   View On Wormbase
Species C. elegans
Genotypeatg-9(ola511[delta AP]) V.
Descriptionola511 is aCRISPR-engineered allele deleting a conserved sorting motif in ATG-9, causing a 2- to 3-fold decrease in LGG-1-containing puncta (and therefore autophagosomes) in the AIY neurites. Reference: Yang S, et al. Neuron. 2022 Mar 2;110(5):824-840.e10.
MutagenNo mutagen
Made byInVivo Biosystems
Laboratory DCR
Reference Yang, S., Park, D., Manning, L., Hill, S. E., Cao, M., Xuan, Z., ... & Colón-Ramos, D. A. (2022). Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9. Neuron, 110(5), 824-840.
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