Strain Information

Name CER554   View On Wormbase
Species C. elegans
Genotypecomt-4(cer157[comt-4p::GFP::H2B]) V.
DescriptionNo obvious phenotype. comt-4(cer157) is a complete deletion of the comt-4 gene (coding sequence + introns), which was replaced by GFP::H2B (Nested CRISPR, Vicencio et al, Genetics 2019), thereby creating a null allele and a transcriptional reporter at the same time. Reference: Martínez-Fernández C, et al. Dis Model Mech. 2022 Mar 1;15(3):dmm049161. doi: 10.1242/dmm.049161. PMID: 35107130
MutagenCrispr/Cas9
Outcrossedx0
Made byCarmen Martínez-Fernández
Laboratory CER
Reference Insights into cisplatin-induced neurotoxicity and mitochondrial dysfunction in Caenorhabditis elegans. Carmen Martínez-Fernández, Milana Bergamino, Alfonso Schiavi, David Brena, Natascia Ventura, Sebastian Honnen, Alberto Villanueva, Ernest Nadal, Julián Cerón Disease Models & Mechanisms, 2022 Mar 1;15(3):dmm049161. doi: 10.1242/dmm.049161.
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