Strain Information
| Name | BR5271 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | byIs162. |
| Description | byIs162 [rab-3p::F3(delta)K280 I277P I380P + myo-2p::mCherry]. Pan-neuronal over-expression of the F3 pro aggregation fragment of the human Tau protein with K280 deleted and two isoleucines to proline substitutions in the hexapeptide motifs of the repeat region (line A). These mutations abrogate the aggregation, making this strain an anti-aggregation control for BR5270. Reference: Fatuouros C, et al. Hum Mol Genet. 2012 Aug 15;21(16):3587-603. |
| Mutagen | Gamma radiation |
| Outcrossed | x5 |
| Made by | C. Fatouros |
| Laboratory | BR |
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