Strain Information

Name BOX163   View On Wormbase
Species C. elegans
Genotypeerm-1(mib9[erm-1[T544D]]) I.
DescriptionHomozygous viable. Modification of endogenous erm-1 locus mimics ERM-1(T544) phosphorylation. Variant affects ERM-1 localization and dynamics. Reduced brood size, increased embryonic and larval lethality. Reference: Ramalho JJ, et al. Development. 2020 Jul 22;147(14):dev188011. PMID: 32586975
Made byJoao J. Ramalho
Laboratory BOX
Reference Ramalho et al., 2020. C-terminal phosphorylation modulates ERM-1 localization and dynamics to control cortical actin organization and support lumen formation during Caenorhabditis elegans development. Development 147, dev188011. doi:10.1242/dev.188011
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