Strain Information
| Name | BB261 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | adr-1(uu49) I; rrf-3(uu56) II; adr-2(uu28) III. |
| Description | Enhanced RNAi. Lacks RNA editing. Vulval bursting. Low brood size. Triple mutants display bursting and low brood size phenotypes not observed in adr-1;adr-2 or rrf-3 parental strains. Reference: Reich DP, et al. Genes Dev. 2018 Feb 1;32(3-4):271-282. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Daniel Reich |
| Laboratory | BB |
| Reference | Reich DP, Tyc KM, and Bass BL (2018). C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway. Genes Dev 32, 271-282. |
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