Strain Information
| Name | BB239 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | adr-1(uu49) I; adr-2(uu28) III. |
| Description | Chemotaxis deficient. Transgenes are silenced in this background. Reference: Reich DP, et al. Genes Dev. 2018 Feb 1;32(3-4):271-282. NOTE: In the referenced publication, irregularities were noted in the adr-1(gv6);adr-2(gv42) null strain, which were ascribed to background mutationsint hat strain. This strain -- adr-1(uu49);adr-2(uu28) -- was generated Crispr/Cas9 targeted mutation and phenotypes are more consistent with another null strain, adr-1(tm668);adr-2(ok735). |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x0 |
| Made by | Daniel Reich |
| Laboratory | BB |
| Reference | Reich, DP, Tyc, KM, and Bass, BL (2018). C. elegans ADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway. Genes Dev 32, 271-282. |
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