Strain Information
| Name | BAN195 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | his-72(bon1[hH3.3::HA + loxP unc-119(+) loxP]) III; his-71(bon2[hH3.3::Myc + loxP unc-119(+) loxP]) X. |
| Description | Endogenous his-72 coding sequence replaced with human H3.3 tagged with HA, and his-71 coding sequence replaced with human H3.3 tagged with Myc. Reference: Piazzesi A, et al. Cell Rep. 2016 Oct 18;17(4):987-996. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x2 |
| Made by | Knudra Transgenics, Antonia Piazzesi |
| Laboratory | BAN |
| Reference | Piazzesi, A. et al. Replication-Independent Histone Variant H3.3 Controls Animal Lifespan through the Regulation of Pro-longevity Transcriptional Programs. Cell Reports 17, 4 (2016) https://doi.org/10.1016/j.celrep.2016.09.074 |
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