Strain Information

Name AV157   View On Wormbase
Species C. elegans
Genotypespo-11(me44)/nT1 [unc-?(n754) let-? qIs50] (IV;V).
DescriptionBalanced heterozygotes are GFP+ Unc and segregate GFP+ Unc (heterozygotes), non-GFP non-Unc spo-11(me44) homozygotes, and dead eggs (nT1 homozygotes). spo-11(me44) homozygotes are viable and produce more than 90% dead eggs (a large fraction of the survivors are males — strong Him phenotype); cytologically they lack chiasmata in diakinesis-stage oocytes and lack RAD-51 foci. Maintain by picking Unc.
MutagenEMS
Outcrossedx>2
Made byGregory Chin
Laboratory AV
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