Strain Information

Name AMP158   View On Wormbase
Species C. elegans
GenotypeohmSi10 II.
DescriptionohmSi10 [eft-3p::TIR1(F79A)::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179). Pan-somatic expression of modified Arabidopsis thaliana TIR1(F79A) tagged with mRuby for super-sensitive auxin-inducible degradation (ssAID) in somatic tissues using 5-Ad-IAA as a ligand. Generated by CRISPR/Cas9 modification of ieSi57 in parental strain CA1200. ohmSi10 previously referred to as ohm10. Reference: Vicencio J, et al. Nature Communications (2025).
MutagenCrispr/Cas9
Outcrossedx4
Made byJeremy Vicencio
Laboratory AMP
Reference Vicencio J, et al., Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology. Nature Communications (2025). [Accepted, pending final publication].
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