Strain Information
| Name | AC456 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | aph-1(tm4743)/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). |
| Description | Heterozygous. Homozygous lethal deletion chromosome balanced by bli-4- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP tm4743 homozygotes (Egl, Mel, adult-onset sterility). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Only heterozygous animals should propagate. aph-1(tm4743) deletion allele was generated by the National BioResource Project of Japan, part of the International C. elegans Gene Knockout Consortium. Reference: Brinkley DM, et al. Genetics. 2024 Jul 8;227(3):iyae076. doi: 10.1093/genetics/iyae076. PMID: 38717968. |
| Mutagen | No mutagen |
| Outcrossed | x5 |
| Made by | Caroline Goutte |
| Laboratory | AC |
| Reference | Brinkley et al. Genetics 2024 Jul 8;227(3) |
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