Strain Information
| Name | ABR161 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | hjIs37; ldrIs1. |
| Description | hjIs37 [vha-6p::mRFP-PTS1 + Cbr-unc-119(+)]. ldrIs1 [dhs-3p::dhs-3::GFP + unc-76(+)]. mRFP targeted to peroxisomes in intestinal cells. dhs-3::GFP is expressed mainly in intestinal cells and localized to intestinal lipid droplets. Derived by crossing parental strains VS10 and LIU1 and outcrossing six times to ABR lab stock of N2. Reference: Papsdorf K, et al. Nat Cell Biol. 2023 May;25(5):672-684. doi: 10.1038/s41556-023-01136-6. 2023. PMID 37127715. |
| Mutagen | No mutagen |
| Outcrossed | x6 |
| Made by | Katharina Papsdorf |
| Laboratory | ABR |
| Reference | Lipid droplets and peroxisomes are co-regulated to drive lifespan extension in response to mono-unsaturated fatty acids. Katharina Papsdorf, Jason W Miklas, Amir Hosseini, Matias Cabruja, Christopher S Morrow, Marzia Savini, Yong Yu, Carlos G Silva-GarcĂa, Nicole R Haseley, Luke Meraz Murphy, Pallas Yao, Elisa de Launoit, Scott J Dixon, Michael P Snyder, Meng C Wang, William B Mair, Anne Brunet Nature Cell Biology, 2023 May;25(5):672-684, doi: 10.1038/s41556-023-01136-6, PMID: 37127715 |
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