Laboratory Information

NameJWW View on WormBase
Allele designationdfw
HeadJeffrey Woodruff
InstitutionUT Southwestern Medical Center, Dallas, TX
Address Dept. of Cell Biology
NL6.110A
6000 Harry Hines Blvd
Dallas 75390
United States
Website www.jeffwoodrufflab.org
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
JWW112 car-1(dfw6[car-1::mMaple]) I. C. elegans mMaple tag inserted at the C-terminus of the endogenous car-1 locus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
JWW166 ifet-1(dfw15[ifet-1::mMaple]) III. C. elegans mMaple tag inserted at the C-terminus of the endogenous ifet-1 locus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
JWW236 mei-1(dfw17[gfp::mei-1]) I; fem-1 (hc17) IV. C. elegans Temperature-sensitive. Maintain at 15C. Female worms at 20C; hermaphrodites at 15C. GFP tag inserted at the N-terminus of the endogenous mei-1 locus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
JWW253 wrdSi3 II; ifet-1(dfw16[ifet-1::mScarlet-I::AID*::3xFlag]) III. C. elegans mScarlet-I::AID*::3xFlag tags inserted at the C-terminus of the endogenous ifet-1 locus. wrdSi3 [sun-1p::TIR1::F2A::mTagBFP2::AID*::NLS::tbb-2 3'UTR] (II:0.77). Germline and early embryo-specific expression of TIR1 co-factor for AID, and tissue-specific AID-tagged blue protein in germline and early embryo nuclei. ifet-1 visualized by mScarlet in oocytes with inducible acute degradation when grown on 4mM auxin. No defect in hermaphrodite embryo viability. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
PHX6862 ifet-1(syb6862[ifet-1(del CHD)::mMaple *dfw15]) III. C. elegans Deletion of the cup homology domain (CHD; 196-217aa) in the endogenously-tagged ifet-1 locus; mMaple tag inserted at the C-terminus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
PHX6886 ifet-1(syb6862[ifet-1(del PolyQ)::mMaple *dfw15]) III. C.elegans Deletion of the Poly Q region (PolyQ; 527-644aa) in the endogenously-tagged ifet-1 locus; mMaple tag inserted at the C-terminus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
PHX6949 ifet-1(syb6949[ifet-1(del NLS)::mMaple *dfw15]) III. C elegans Deletion of the Nuclear Localization Sequence (NLS; 220-235aa) in the endogenously-tagged ifet-1 locus; mMaple tag inserted at the C-terminus. No embryonic viability defect in hermaphrodites. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
PHX6954 ifet-1(syb6862[ifet-1(del CC)::mMaple *dfw15]) III. C.elegans Deletion of the coiled coil domain (CC; 664-691aa) in the endogenously-tagged ifet-1 locus; mMaple tag inserted at the C-terminus. Reference: Bhatia P, et al. Life Sci Alliance. 2025 May 29;8(8):e202503387. doi: 10.26508/lsa.202503387. PMID: 40441896.
This laboratory hasn't submitted any alleles to the CGC.