Strain Information
| Name | WBM1481 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | let-363(wbm46[AID::let-363]) I. |
| Description | Auxin-Inducible Degron (AID) tag was inserted into the endogenous let-363 coding sequence via CRISPR/Cas9. This strain can be combined with TIR1-expressing strains to induce degradation of LET-363. Reference: Smith HJ, et al. PLoS Genetic. 2023 Sep 18;19(9):e1010938. doi: 10.1371/journal.pgen.1010938. PMID: 37721956. |
| Mutagen | Crispr/Cas9 |
| Outcrossed | x6 |
| Made by | Anne Lanjuin, Hannah J Smith, Aditi Prabhakar |
| Laboratory | WBM |
| Reference | Smith HJ, Lanjuin A, Sharma A, Prabhakar A, Nowak E, et al. (2023) Neuronal mTORC1 inhibition promotes longevity without suppressing anabolic growth and reproduction in C. elegans. PLOS Genetics 19(9): e1010938. https://doi.org/10.1371/journal.pgen.1010938 |
Sign in
or
register an account if you want to order this strain.