Strain Information
| Name | VT3809 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | alg-1(ma443) X. |
| Description | Maintain at 20C. ma443 is a G199S substitution mimicking human AGO1 G199S mutation. Adult ma443 mutants exhibit reduced or absent COL-19::GFP expression in Hyp7 cells. Defective vulval development and adult lethality are more penetrant at restrictive temperature (25C). Reference: Duan Y, et al. Proc Natl Acad Sci USA. 2024 Mar 5;121(10):e2308255121. doi: 10.1073/pnas.2308255121. PMID: 38412125. |
| Mutagen | No mutagen |
| Outcrossed | x1 |
| Made by | Victor Ambros |
| Laboratory | VT |
| Reference | PMID: 38412125 |
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