Strain Information

Name VK3835   View On Wormbase
Species C. elegans
Genotypeatg-3(bp412) IV; vkIs3785 X.
DescriptionvkIs3785 [nhx-2p::gfp::lgg-1::mKate2]; inserted into LG X. Fluorescent reporter for autophagic flux. Stronger GFP expression in intestine than in wild-type background. Reference: Dawson ZD, et al. Autophagy rep. 2024;3(1):2371736. doi: 10.1080/27694127.2024.2371736. PMID: 39070663.
MutagenNo mutagen
Outcrossedx6
Made byZachary D. Dawson
Laboratory VK
Reference Zachary D. Dawson, Hemalatha Sundaramoorthi, Suk Regmi, Bo Zhang, Stephanie Morrison, Sara M. Fielder, Jessie R. Zhang, Hieu Hoang, David H. Perlmutter, Cliff J. Luke, Gary A. Silverman & Stephen C. Pak (2024) A fluorescent reporter for rapid assessment of autophagic flux reveals unique autophagy signatures during C. elegans post-embryonic development and identifies compounds that modulate autophagy, Autophagy Reports, 3:1, 2371736, DOI: 10.1080/27694127.2024.2371736
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