Strain Information
| Name | UY99 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | maIs105 V; alg-1(zen18) X. |
| Description | Maintain at 20C. maIs105 [col-19::GFP] V. zen18 is a H751L substitution mimicking human AGO1 H751L mutation. Adult zen18 mutants exhibit reduced or absent COL-19::GFP expression in Hyp7 cells. Defective vulval development and adult lethality are more penetrant at restrictive temperature (25C). Reference: Duan Y, et al. Proc Natl Acad Sci USA. 2024 Mar 5;121(10):e2308255121. doi: 10.1073/pnas.2308255121. PMID: 38412125. |
| Mutagen | No mutagen |
| Outcrossed | x1 |
| Made by | Anna Zinovyeva |
| Laboratory | VT |
| Reference | PMID: 38412125 |
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