Strain Information
| Name | UL4285 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | unc-68(le4285) V. |
| Description | The UNC-68a N2441S missense mutation (le4285) corresponds to a human myopathic variant, RyR1:p.N2342S. Subtle effects on locomotion, and altered response to halothane and aldicarb. Reference: Graham B, et al. Front. Genet. 2020; 11:37. doi: 10.3389/fgene.2020.00037 PMID: 32174957 |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | Alex Jubb |
| Laboratory | UL |
| Reference | Graham B, Shaw M-A and Hope IA (2020) Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro- Muscular Function. Front. Genet. 11:37. doi: 10.3389/fgene.2020.00037 |
Sign in
or
register an account if you want to order this strain.