Strain Information
| Name | UL4239 View On Wormbase |
|---|---|
| Species | C. elegans |
| Genotype | unc-68(le4239) V. |
| Description | The UNC-68a R169C missense mutation (le4239) corresponds to a human myopathic variant, RyR1:p.R163C. Subtle effects on locomotion, and altered response to halothane and aldicarb. Reference: Graham B, et al. Front. Genet. 2020; 11:37. doi: 10.3389/fgene.2020.00037 PMID: 32174957 |
| Mutagen | No mutagen |
| Outcrossed | x0 |
| Made by | David Pertab |
| Laboratory | UL |
| Reference | Graham B, Shaw M-A and Hope IA (2020) Single Amino Acid Changes in the Ryanodine Receptor in the Human Population Have Effects In Vivo on Caenorhabditis elegans Neuro- Muscular Function. Front. Genet. 11:37. doi: 10.3389/fgene.2020.00037 |
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